Ixabepilone 0160 It has minimal activity (IC50

It has minimal activity (IC50 >1 µM) against HDAC4

Miltefosine targets cellular membranes

thus triggering the unfolded protein response (UPR)

Chemical Name: ({2-[(3-aminopropyl)amino]ethyl}sulfanyl)phosphonic acid

which is a DNA minor groove binder used fluorochrome for visualizing cellular DNA

Ixabepilone 0160 It has minimal activity (IC50Ixabepilone (also known as azaepothilone B, or BMS 247550) is an orally bioavailable microtubule inhibitor. Ixabepilone was a semisynthetic analogue of epothilone B with antineoplastic activity. Ixabepilone binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2 M phase of the cell cycle and inducing tumor cell apoptosis. This agent demonstrates antineoplastic activity against taxane