Tamibarotene - CAS# 94497-51-5 oxifen citrate thereby blocking VEGF-stimulated endothelial cell

thereby blocking VEGF-stimulated endothelial cell proliferation and migration and reducing tumor vessel permeability

JW74 induces reduced cell growth in all three tested cell lines

InChiKey: ACGUYXCXAPNIKK-UHFFFAOYSA-N

Formula: C22H22N6O3

specific and brain-penetrant Lysine Specific Demethylase-1 (LSD1) inhibitor

Tamibarotene - CAS# 94497-51-5 oxifen citrate thereby blocking VEGF-stimulated endothelial cellTamibarotene, also known as SY 1425, is an orally active, synthetic retinoid, developed to overcome all trans retinoic acid (ATRA) resistance, with potential antineoplastic activity. As a specific retinoic acid receptor (RAR) alpha beta agonist, tamibarotene is approximately ten times more potent than ATRA in inducing cell differentiation and apoptosis in HL 60 (human promyelocytic leukemia) cell lines in vitro. Due to a lower affinity for cellular