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Efinaconazole - CAS# 164650-44-6 Size:Solid 10 mg 2-methylpropan-2-amine

SKU: 71869216651

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Efinaconazole - CAS# 164650-44-6 Size:Solid 10 mg 2-methylpropan-2-amineEfinaconazole is a triazole antifungal. It is approved for use in Canada and the USA as a 10% topical solution for the treatment of onychomycosis (fungal infection of the nail). Efinaconazole acts as a 14 demethylase inhibitor. Efinaconazole inhibits fungal lanosterol 14 demethylase involved in the biosynthesis of ergosterol, a constituent of fungal cell membranes. Efinaconazole has been shown to be active against isolates of the following

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Description

2-methylpropan-2-amine

InChiKey: BXKYFUGAAFLYJL-BXGYHSFXSA-N

an enzyme often overexpressed in cancer cells

Chemical Name: 2-(furan-2-ylmethylsulfinyl)-N-[(Z)-4-[4-(piperidin-1-ylmethyl)pyridin-2-yl]oxybut-2-enyl]acetamide

whereas inhibits total SAPK/JNK activity with an IC50 of 3–10 μM

Efinaconazole - CAS# 164650-44-6 Size:Solid 10 mg 2-methylpropan-2-amineEfinaconazole is a triazole antifungal. It is approved for use in Canada and the USA as a 10% topical solution for the treatment of onychomycosis (fungal infection of the nail). Efinaconazole acts as a 14 demethylase inhibitor. Efinaconazole inhibits fungal lanosterol 14 demethylase involved in the biosynthesis of ergosterol, a constituent of fungal cell membranes. Efinaconazole has been shown to be active against isolates of the following

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