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Fluvastatin D6 Sodium Catalog No.:M8292-10 is discovered to inhibit JNK

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Fluvastatin D6 Sodium Catalog No.:M8292-10 is discovered to inhibit JNKFluvastatin D6 sodium (XU 62 320 D6) is deuterium labeled Fluvastatin sodium. Fluvastatin sodium (XU 62320) is a first fully synthetic, competitive HMG CoA reductase inhibitor with an IC50 of 8 nM. Product information CAS Number: 2070009 35 5 Molecular Weight: 439. 48 Formula: C24H25FNNaO4 Chemical Name: sodium (3R, 5S, 6E) 7 [3 (4 fluorophenyl) 1 [(1, 1, 1, 3, 3, 3 H)propan 2 yl] 1H indol 2 yl] 3, 5 dihydroxyhept 6 enoate Smiles:

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Description

is discovered to inhibit JNK kinase by broad-base kinase selectivity profiling of a library of acrylamide kinase inhibitors based on the structure of imatinib using the KinomeSca approach

R112 does not inhibit phosphorylation of the Lyn target Syk (Y352)

Stephenson J

InChi: InChI=1S/C21H20O10/c22-7-15-18(26)19(27)20(28)21(31-15)30-11-5-13(24)16-14(6-11)29-8-12(17(16)25)9-1-3-10(23)4-2-9/h1-6

transition zone and agonist binding site while binding to α7 nAChR

Fluvastatin D6 Sodium Catalog No.:M8292-10 is discovered to inhibit JNKFluvastatin D6 sodium (XU 62 320 D6) is deuterium labeled Fluvastatin sodium. Fluvastatin sodium (XU 62320) is a first fully synthetic, competitive HMG CoA reductase inhibitor with an IC50 of 8 nM. Product information CAS Number: 2070009 35 5 Molecular Weight: 439. 48 Formula: C24H25FNNaO4 Chemical Name: sodium (3R, 5S, 6E) 7 [3 (4 fluorophenyl) 1 [(1, 1, 1, 3, 3, 3 H)propan 2 yl] 1H indol 2 yl] 3, 5 dihydroxyhept 6 enoate Smiles:

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