FR 180204 Size:Solid 2 mg Please note: exact ratio for

Please note: exact ratio for use and transfection efficiency is dependent on cell line used

Emerging roles of cysteine cathepsins in disease and their potential as drug targets

2 L/kg) in the dogs

and induction of DNA damage

It has very weak or no activity targeting the other HDACs (2-40 µM)

FR 180204 Size:Solid 2 mg Please note: exact ratio forFR180204 is a novel and selective inhibitor of extracellular signal regulated kinase (ERK), which may be a potential new therapy for rheumatoid arthritis. FR180204 showed activity to inhibit ERKs (IC50 values are 0. 14 and 0. 31 M for ERK2 and ERK1 respectively). Product information CAS Number: 865362 74 9 Molecular Weight: 327. 34 Formula: C18H13N7 Synonym: FR180204 FR 180204 Chemical Name: 5 {2 phenylpyrazolo[1,5 a]pyridin 3 yl} 2H pyrazolo[3,4