Tuberin(Phospho Thr1462) Polyclonal Antibody, 50ul Plasma Intermediate filamentents

Intermediate filamentents

The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex

The PIAS family contains a conserved RING domain that has been linked to a function as a small ubiquitin-related modifier (SUMO) ligase

The process is simpler in prokaryotes which have only three initiation factors (IF1

and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins

Tuberin(Phospho Thr1462) Polyclonal Antibody, 50ul Plasma Intermediate filamententsMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.