HSH2D Rabbit Polyclonal Antibody, 100ul Electrophoresis & Labeling The encoded protein is a

The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family

The protein encoded by this gene is an adapter for the FYN protein and LCP2 signaling cascades in T-cells

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The protein encoded by this gene contains a SH2 domain and a SOCS box domain

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HSH2D Rabbit Polyclonal Antibody, 100ul Electrophoresis & Labeling The encoded protein is aT cell activation requires 2 signals: recognition of antigen by the T cell receptor (see TCR; MIM 186880) and a costimulatory signal provided primarily by CD28 (MIM 186760) in naive T cells. HSH2 is a target of both of these signaling pathways (Greene et al. 2003