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FOLR3 Polyclonal Antibody, 50ul Immune Cell Preparation Ubiquitination of type II deiodinase

SKU: 99158174752

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FOLR3 Polyclonal Antibody, 50ul Immune Cell Preparation Ubiquitination of type II deiodinaseThis gene encodes a member of the folate receptor (FOLR) family of proteins, which have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5 methyltetrahydrofolate to the interior of cells. Expression of this gene may be elevated in ovarian and primary peritoneal carcinoma. This gene is present in a gene cluster on chromosome 11. Alternative splicing results in multiple transcript variants.

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Description

Ubiquitination of type II deiodinase by the encoded protein is an important regulatory step in thyroid hormone signalling

This gene is highly conserved across mammalian species and retains the heptanucleotide (GGGAAAC) and pseudoknot elements required for -1 FS

Alternatively spliced transcript variants encoding different isoforms of this gene have been described

Mammalian mitochondrial ribosomal protein L 40 (39S ribosomal protein L40 mitochondrial) is encoded by nuclear gene MRPL40 and help in protein synthesis within the mitochondrion

It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase

FOLR3 Polyclonal Antibody, 50ul Immune Cell Preparation Ubiquitination of type II deiodinaseThis gene encodes a member of the folate receptor (FOLR) family of proteins, which have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5 methyltetrahydrofolate to the interior of cells. Expression of this gene may be elevated in ovarian and primary peritoneal carcinoma. This gene is present in a gene cluster on chromosome 11. Alternative splicing results in multiple transcript variants.

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