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BNIP-3 Polyclonal Antibody, 100ul[BT-AP00948] Deep Well Plates In response to DNA damage

SKU: 97294874047

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BNIP-3 Polyclonal Antibody, 100ul[BT-AP00948] Deep Well Plates In response to DNA damageBNIP3 (BCL2 interacting protein 3) is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro apoptotic factor. The encoded protein interacts with anti apoptotic proteins, including the E1B 19 kDa protein and Bcl2. BNIP3 is silenced in tumors by DNA methylation.

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Description

In response to DNA damage

metabolism

possibly by inhibition of mRNA stabilization

The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line

Several related pseudogenes have also been identified

BNIP-3 Polyclonal Antibody, 100ul[BT-AP00948] Deep Well Plates In response to DNA damageBNIP3 (BCL2 interacting protein 3) is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro apoptotic factor. The encoded protein interacts with anti apoptotic proteins, including the E1B 19 kDa protein and Bcl2. BNIP3 is silenced in tumors by DNA methylation.

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