TM199 Rabbit Polyclonal Antibody, 20ul Culture Plate Inserts TOP2A encodes a DNA topoisomerase

TOP2A encodes a DNA topoisomerase

The encoded enzyme contains a hydrolase domain at the N-terminal portion

This difference in size is largely due to an increase in the number of subdomains

PGBD1 product is specifically expressed in the brain

The encoded protein is one of three proteins found in the flavoprotein fraction of the complex

TM199 Rabbit Polyclonal Antibody, 20ul Culture Plate Inserts TOP2A encodes a DNA topoisomeraseThe protein encoded by this gene has been observed to localize to the endoplasmic reticulum (ER) Golgi intermediate compartment (ERGIC) and coat protein complex I (COPI) in some human cells. The encoded protein shares some homology with the yeast protein Vma12. Defects in this gene are a cause of congenital disorder of glycosylation type IIp.