IOD2 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) and RNA splicing

and RNA splicing

and are involved in intracellular trafficking

and regulates centriole duplication during the cell cycle

Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN7)

This gene is mutated in congenital disorder of glycosylation type Ik

IOD2 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) and RNA splicingThe protein encoded by this gene belongs to the iodothyronine deiodinase family. It catalyzes the conversion of prohormone thyroxine (3,5,3',5' tetraiodothyronine, T4) to the bioactive thyroid hormone (3,5,3' triiodothyronine, T3) by outer ring 5' deiodination. This gene is widely expressed, including in thyroid, placenta, pituitary and brain. It is thought to be responsible for the 'local' production of T3, and thus important in influencing thyroid