SYP Polyclonal Antibody, 100ul Cell Culture Flasks Defects in this gene have

Defects in this gene have been associated with PBD complementation group 11 (PBD-CG11) disorders

The protein encoded by this gene contains a homeobox domain and may be involved in the morphogenesis of the central nervous system

The other less-related subfamily includes KRTHB2

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The p53/TP53-cofactor and actin activator activities are regulated via its subcellular location

SYP Polyclonal Antibody, 100ul Cell Culture Flasks Defects in this gene haveSYP encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. Synaptophysin also binds cholesterol and is thought to direct targeting of vesicle associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X linked mental retardation (XLMR).