MCF2 Polyclonal Antibody, 20ul NGS Oligos Defects in this gene are

Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam

and this DMR is commonly found in imprinted genes and correlates with transcript expression

and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins

GO annotations related to this gene include RNA binding and U2 snRNA binding

Mad1 and Mad4

MCF2 Polyclonal Antibody, 20ul NGS Oligos Defects in this gene areThe oncogenic protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that exerts control over some members of the Rho family of small GTPases. Several transcript variants encoding different isoforms have been found for this gene. These isoforms exhibit different expression patterns and varying levels of GEF activity.