ARRDC3 Polyclonal Antibody, 100ul Gloves Known to interact with Filamin

Known to interact with Filamin 1

The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation

The protein is thought to be involved in cell motility| phagocytosis| membrane trafficking and mitogenesis

The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1)| and induces cell apoptosis

Disruption of this gene may be associated with cerebral palsy

ARRDC3 Polyclonal Antibody, 100ul Gloves Known to interact with FilaminARRDC3 (arrestin domain containing 3) encodes a member of the arrestin family of proteins, which regulate G protein mediated signaling. The encoded protein is thought to act as a regulator of breast cancer growth and progression by binding to a phosphorylated form of integrin beta4, a tumor related antigen, targeting the integrin for internalization and degradation.