ZFY27 Rabbit Polyclonal Antibody, 100ul Molecular Sciences In humans| two ubiquitous plastin

In humans| two ubiquitous plastin isoforms (L and T) have been identified

and it is thought to play an important role in mediating p53-dependent apoptosis

and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al

It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer

such as TCR signaling

ZFY27 Rabbit Polyclonal Antibody, 100ul Molecular Sciences In humans| two ubiquitous plastinThis gene encodes a protein with several transmembrane domains a Rab11 binding domain and a lipid binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia however the pathogenicity of the mutation which may simply represent a polymorphism is unclear.