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ErbB-3 Monoclonal Antibody, 50ul[BT-MCA0503] Organelle Studies a less severe immunodeficiency disorder

SKU: 88958724504

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ErbB-3 Monoclonal Antibody, 50ul[BT-MCA0503] Organelle Studies a less severe immunodeficiency disorderThis gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the

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Description

a less severe immunodeficiency disorder

Caspase 3 is reported to be involved in the proteolytic processing of this protein

The encoded protein is localized to the endoplasmic reticulum

It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK)

These disorders have at least 14 complementation groups

ErbB-3 Monoclonal Antibody, 50ul[BT-MCA0503] Organelle Studies a less severe immunodeficiency disorderThis gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the

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