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Ku-70 (Acetyl Lys317) Polyclonal Antibody, 20ul Peptide Modification an additional IL2-specific alpha subunit

SKU: 83663613080

4.2
PLN111.00 PLN136.00

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Ku-70 (Acetyl Lys317) Polyclonal Antibody, 20ul Peptide Modification an additional IL2-specific alpha subunitThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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Description

an additional IL2-specific alpha subunit necessary for high affinity IL2 binding

These mutations have been shown to cause diverse changes in the pattern of DNA methylation

It has now been found that this gene is involved in the regulation of many NR and non-NR activities| including metabolism| adipogenesis and chromatin organization

Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism

The encoded protein is localized to mitochondria and may also play a neuroprotective role as a molecular chaperone

Ku-70 (Acetyl Lys317) Polyclonal Antibody, 20ul Peptide Modification an additional IL2-specific alpha subunitThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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