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STEAP1 Polyclonal Antibody, 100ul ssDNA Synthesis This gene encodes a cytokine

SKU: 80940767180

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STEAP1 Polyclonal Antibody, 100ul ssDNA Synthesis This gene encodes a cytokineSTEAP1 is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell cell junctions.

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Description

This gene encodes a cytokine receptor-like factor that may negatively regulate cell cycle progression at the G0/G1 phase

CERKL was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease

This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat

The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors

The extracellular portion binds structures with a high mannose content and has been shown to recognize several pathogens

STEAP1 Polyclonal Antibody, 100ul ssDNA Synthesis This gene encodes a cytokineSTEAP1 is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell cell junctions.

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