PC-PLD1(Phospho Thr147) Polyclonal Antibody, 20ul In vitro Assessment The encoded preproprotein is proteolytically

The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide

Expression was also detected in many epithelial tumor cell lines

Mature meprins are oligomers of evolutionarily related

Two alternatively spliced transcripts encoding the same isoform have been reported

Both N- and C-terminal domains are required for transcriptional activation

PC-PLD1(Phospho Thr147) Polyclonal Antibody, 20ul In vitro Assessment The encoded preproprotein is proteolyticallyThis gene encodes a phosphatidylcholine specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties.