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EGF Receptor(Phospho-Tyr1045) Rabbit Polyclonal Antibody, 50ul Shakers subunit:Component of some SAGA transcription

SKU: 80928077396

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EGF Receptor(Phospho-Tyr1045) Rabbit Polyclonal Antibody, 50ul Shakers subunit:Component of some SAGA transcriptionThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

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Description

subunit:Component of some SAGA transcription coactivator-HAT complex

IL-22 is a ligand for CRF2-4

Other variants exist

The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases

Alternative splicing results in multiple transcript variants| some of which encode distinct isoforms| including a protease packaged into dense core granules (PC5A) and a type 1 membrane bound protease (PC5B)

EGF Receptor(Phospho-Tyr1045) Rabbit Polyclonal Antibody, 50ul Shakers subunit:Component of some SAGA transcriptionThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

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