EGF Receptor(Phospho-Tyr1068) Rabbit Polyclonal Antibody, 100ul Shakers Contributes to cell motility by

Contributes to cell motility by controlling actin dynamics

Transcript variants encoding different preproprotein isoforms have been described for this gene

72 kDa type IV collagenase encoded by MMP2 is a gelatinase A

PTM:Ser-376 and Thr-581 phosphorylation is required for kinase activity

Among its related pathways are RNA transport and mRNA surveillance pathway

EGF Receptor(Phospho-Tyr1068) Rabbit Polyclonal Antibody, 100ul Shakers Contributes to cell motility byThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.