BL1S3 Rabbit Polyclonal Antibody, 20ul Vortex Mixer tramtrack and bric-a-brac) domain

tramtrack and bric-a-brac) domain

a central proline/serine rich (PS) domain

The chondroitin sulfate proteoglycan NG2 is a type I membrane protein expressed by subpopulations of glia including oligodendroglial precursor cells and a variety of tumor cells

TRAF proteins associate with| and mediate the signal transduction from members of the TNF receptor superfamily

Multiple alternatively spliced transcript variants have been identified in this gene

BL1S3 Rabbit Polyclonal Antibody, 20ul Vortex Mixer tramtrack and bric-a-brac) domainThis gene encodes a protein that is a component of the BLOC1 multi subunit protein complex. This complex is necessary for the biogenesis of specialized organelles of the endosomal lysosomal system, including platelet dense granules and melanosomes. Mutations in this gene cause Hermansky Pudlak syndrome 8, a disease characterized by lysosomal storage defects, bleeding due to platelet storage pool deficiency, and oculocutaneous albinism.