JAK1 Polyclonal Antibody, 50ul[BT-AP04684] Cell Separation and Collection This gene is tandemly arrayed

This gene is tandemly arrayed on chromosome 2| in a head-to-head orientation with family member ABCG8

In addition to its ability to bind BRCA1 in vivo and in vitro

May play a role in a signaling cascade by enhancing the kinase activity of SRC

Mutations in this gene may be associated with susceptibility to carotid artery disease

Female mice lacking ZP2 (zona pellucida glycoprotein 2) do not form a stable zona matrix and are sterile

JAK1 Polyclonal Antibody, 50ul[BT-AP04684] Cell Separation and Collection This gene is tandemly arrayedJAK1 encodes a membrane protein that is a member of a class of protein tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase related domain immediately N terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon alpha beta and interferon gamma signal transduction. Alternative splicing results in multiple transcript