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3BP2 Polyclonal Antibody, 50ul Polyclonal Antibody Preparation While it may be a

SKU: 7477609026

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DKK185.00 DKK232.00

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3BP2 Polyclonal Antibody, 50ul Polyclonal Antibody Preparation While it may be aThe protein encoded by this gene has an N terminal pleckstrin homology (PH) domain an SH3 binding proline rich region and a C terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T natural killer (NK) and basophilic cells. Mutations in this gene result in cherubism. Multiple

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Description

While it may be a target for immunotherapy| the function of this gene is unknown

can act both as an aminopeptidase and as an endopeptidase

Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia

The gene is expressed in normal stomach and testis

This KRT6 gene in particular encodes the most abundant isoform

3BP2 Polyclonal Antibody, 50ul Polyclonal Antibody Preparation While it may be aThe protein encoded by this gene has an N terminal pleckstrin homology (PH) domain an SH3 binding proline rich region and a C terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T natural killer (NK) and basophilic cells. Mutations in this gene result in cherubism. Multiple

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