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BRD2 Polyclonal Antibody, 50ul Cell Separation and Collection tissue specificity:Predominantly expressed in thymus

SKU: 6842657542

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BRD2 Polyclonal Antibody, 50ul Cell Separation and Collection tissue specificity:Predominantly expressed in thymusThis gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine 12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21. 3, but sequence comparison

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Description

tissue specificity:Predominantly expressed in thymus

and thus regulate separate functions in cell cycle

MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking

It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex that also couples to neurotransmitter receptors in the brain and whereby channel activation can inhibit action potential firing by hyperpolarizing the plasma membrane

This phosphorylation may play a role in RCC1 interaction with chromatin and its RanGEF activity

BRD2 Polyclonal Antibody, 50ul Cell Separation and Collection tissue specificity:Predominantly expressed in thymusThis gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine 12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21. 3, but sequence comparison

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