Human Dynein Heavy Chain 17, Axonemal, DNAH17 ELISA Kit, 96T Mammalian Expression The transforming acidic coiled-coil-containing protein

The transforming acidic coiled-coil-containing protein 3 is a motor spindle protein that may play a role in stabilization of the mitotic spindle

Mutations in this gene cause peroxisome biogenesis disorders of complementation group 4 and complementation group 6

and sgRNA library oligos

Two alternatively spliced transcript variant encoding distinct isoforms have been reported

regulating cellular cholesterol homoeostasis

Human Dynein Heavy Chain 17, Axonemal, DNAH17 ELISA Kit, 96T Mammalian Expression The transforming acidic coiled-coil-containing proteinForce generating protein component of the outer dynein arms (ODAs) in the sperm flagellum. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force producing power stroke is thought to occur on release of ADP (Probable). Plays a major role in sperm motility, implicated in sperm flagellar assembly and beating (PubMed: 31178125).