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Human Interleukin 1 Receptor Antagonist, IL1RA ELISA Kit, 96T Gel & Buffers A 117 kb microdeletion at

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Human Interleukin 1 Receptor Antagonist, IL1RA ELISA Kit, 96T Gel & Buffers A 117 kb microdeletion at

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Description

A 117 kb microdeletion at the 5' end of the HOXD gene cluster| which includes this gene and the HOXD9-HOXD13 genes| causes synpolydactyly| a dominantly inherited disease resulting in limb malformation

It is expressed at low levels in the cytoplasm of pro-B and pre-B cells and present on the cell surface only at mature stages of B-cell differentiation

the activity of the encoded protein depends on the protein binding partner

Seems not to be essential for early virus-activated host defense in vaginal infection

Incorporated into fibronectin-containing matrix fibers

Human Interleukin 1 Receptor Antagonist, IL1RA ELISA Kit, 96T Gel & Buffers A 117 kb microdeletion at

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