SMG9 Polyclonal Antibody, 100ul Isothermal Amplification Mutations in the promoter region

Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers

This gene encodes a protein that belongs to the Rho GTPase family

Y-box-binding protein 2 binds to a Y-box element in the promoters of certain genes but also binds to mRNA transcribed from these genes

which houses over 500 genes and is the second smallest human chromosome

Like calmodulin

SMG9 Polyclonal Antibody, 100ul Isothermal Amplification Mutations in the promoter regionThis gene encodes a regulatory subunit of the SMG1 complex, which plays a critical role in nonsense mediated mRNA decay (NMD). Binding of the encoded protein to the SMG1 complex kinase scaffold protein results in the inhibition of its kinase activity. Mutations in this gene cause a multiple congenital anomaly syndrome in human patients, characterized by brain malformation, congenital heart disease and other features.