SREBP-1 Polyclonal Antibody, 50ul[BT-AP08552] Apoptosis & Autophagy The protein encoded by MED14

The protein encoded by MED14 (mediator complex subunit 14) is a subunit of the CRSP (cofactor required for SP1 activation) complex

ATF3 encodes a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors

The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1

The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1

It binds to vitamin D and its plasma metabolites and transports them to target tissues

SREBP-1 Polyclonal Antibody, 50ul[BT-AP08552] Apoptosis & Autophagy The protein encoded by MED14SREBF1 encodes a transcription factor that binds to the sterol regulatory element 1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. Sterol regulatory element binding protein 1 is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by