NEC1 Rabbit Polyclonal Antibody, 100ul Glassware Alternative splicing of EXO1 results

Alternative splicing of EXO1 results in three transcript variants encoding two different isoforms

This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism| synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney

The gamma subunits contain the active site of the enzyme

also known as AN

Several upstream open reading frames (uORFs) have been identified| which repress the translation of the dORF| and two of which can encode small mitochondrial membrane proteins

NEC1 Rabbit Polyclonal Antibody, 100ul Glassware Alternative splicing of EXO1 resultsThis gene encodes a member of the subtilisin like proprotein convertase family which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to subcellular compartments where a second autocatalytic even takes place and the