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EMAL4 Rabbit Polyclonal Antibody, 100ul Endonucleases & Exonucleases Mutations at this locus have

SKU: 6147990748

4.6
PLN123.75 PLN166.75

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EMAL4 Rabbit Polyclonal Antibody, 100ul Endonucleases & Exonucleases Mutations at this locus haveThis gene is a member of the echinoderm microtubule associated protein like family. The encoded WD repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene which generates EML4 ALK fusion transcripts is one of the primary mutations associated with non small cell lung cancer. Alternative splicing of this gene results in two transcript variants.

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Description

Mutations at this locus have been associated with microcephaly| seizures| and developmental delay

This innovative and easy-to-use kit allows for quick and reliable detection of IL-10 levels in mouse samples

Mutations in this gene result in Currarino syndrome

Gene expression is high during fetal development and in most tumors| yet low in adult tissues

Related pseudogenes have been defined on chromosomes 8 and 20

EMAL4 Rabbit Polyclonal Antibody, 100ul Endonucleases & Exonucleases Mutations at this locus haveThis gene is a member of the echinoderm microtubule associated protein like family. The encoded WD repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene which generates EML4 ALK fusion transcripts is one of the primary mutations associated with non small cell lung cancer. Alternative splicing of this gene results in two transcript variants.

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