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EKLF (Acetyl Lys274) Rabbit Polyclonal Antibody, 20ul Antibody Humanization Related pseudogenes have been defined

SKU: 6147632847

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EKLF (Acetyl Lys274) Rabbit Polyclonal Antibody, 20ul Antibody Humanization Related pseudogenes have been definedThis gene encodes a hematopoietic specific transcription factor that induces high level expression of adult beta globin and other erythroid genes. The zinc finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss of function mutations in this gene result in the dominant In(Lu) blood phenotype.

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Description

Related pseudogenes have been defined on the X chromosome

The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene

Binding to he LCK SH3 domain occurs constitutively

the rate-limiting enzyme in bile acid synthesis

an essential step in the biosynthesis of PtdInsPs (Barylko et al

EKLF (Acetyl Lys274) Rabbit Polyclonal Antibody, 20ul Antibody Humanization Related pseudogenes have been definedThis gene encodes a hematopoietic specific transcription factor that induces high level expression of adult beta globin and other erythroid genes. The zinc finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss of function mutations in this gene result in the dominant In(Lu) blood phenotype.

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