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FAK(Phospho Tyr577) Polyclonal Antibody, 50ul Liquid Handling &Storage Several alternatively spliced transcripts have

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FAK(Phospho Tyr577) Polyclonal Antibody, 50ul Liquid Handling &Storage Several alternatively spliced transcripts haveThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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Description

Several alternatively spliced transcripts have been described

Mutations in this gene can result in B cell deficiency and agammaglobulinemia

An important paralog of this gene is HSH2D

MOB4 was identified based on its similarity with the mouse counterpart

PKC family members also serve as major receptors for phorbol esters

FAK(Phospho Tyr577) Polyclonal Antibody, 50ul Liquid Handling &Storage Several alternatively spliced transcripts haveThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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