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HECW1 Polyclonal Antibody, 50ul Antibodies Together with PCBP-1

SKU: 61289660445

4.3
USD162.00 USD184.00

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HECW1 Polyclonal Antibody, 50ul Antibodies Together with PCBP-1E3 ubiquitin protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.,pathway: Protein modification; protein ubiquitination.,Contains 1 C2 domain.,Contains 1 HECT (E6AP type E3 ubiquitin protein ligase) domain.,Contains 2 WW

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Description

Together with PCBP-1

The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol

This gene is found within an intron of another gene| bladder cancer associated protein| but on the opposite strand

PTM:N- and O-glycosylated

The length and aperture of the tube can also be customized

HECW1 Polyclonal Antibody, 50ul Antibodies Together with PCBP-1E3 ubiquitin protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.,pathway: Protein modification; protein ubiquitination.,Contains 1 C2 domain.,Contains 1 HECT (E6AP type E3 ubiquitin protein ligase) domain.,Contains 2 WW

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