Stat2 (Acetyl Lys384) Rabbit Polyclonal Antibody, 50ul In vitro Assessment TACC3 encodes a member of

TACC3 encodes a member of the transforming acidic colied-coil protein family

Inward rectifier potassium channel 2

MARK proteins phosphorylate MAPs within their microtubule binding domains

This protein does not bind DNA directly

Appears to function synergistically with RBM14 as a transcriptional coactivator

Stat2 (Acetyl Lys384) Rabbit Polyclonal Antibody, 50ul In vitro Assessment TACC3 encodes a member ofSignal transducer and activator of transcription that mediates signaling by type I IFNs (IFN alpha and IFN beta). Following type I IFN binding to cell surface receptors Jak kinases (TYK2 and JAK1) are activated leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize associate with ISGF3G IRF 9 to form a complex termed ISGF3 transcription factor that enters the nucleus. ISGF3 binds to the IFN stimulated response