PCSK5 Rabbit Polyclonal Antibody, 50ul Drying & Desiccation Altered copy number and activity

Altered copy number and activity of this gene have been observed in a number of human cancers

The most striking difference between the RAP and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins

The phenotype of malignant melanomas in vivo depends on the global expression of stimulatory or inhibitory factors generated in both the tumors cells and their environment

May play a role in lymphocyte adhesion

Among its related pathways are DNA Double-Strand Break Repair and Fanconi anemia pathway

PCSK5 Rabbit Polyclonal Antibody, 50ul Drying & Desiccation Altered copy number and activityThis gene encodes a member of the subtilisin like proprotein convertase family which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER. It then sorts to the trans Golgi network where a second autocatalytic event takes place and the