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PLCA Polyclonal Antibody, 50ul Bio-Reaction Tube Variations in this gene may

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PLCA Polyclonal Antibody, 50ul Bio-Reaction Tube Variations in this gene mayThis gene encodes an enzyme that converts lysophosphatidic acid (LPA) into phosphatidic acid (PA). LPA and PA are two phospholipids involved in signal transduction and in lipid biosynthesis in cells. This enzyme localizes to the endoplasmic reticulum. This gene is located in the class III region of the human major histocompatibility complex. Alternative splicing results in two transcript variants encoding the same protein.

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Description

Variations in this gene may increase the risk of prostate cancer

Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy| it may play a role in that disease also

This gene encodes a mitochondrial protein that interacts with reticulon 4| which is a potent inhibitor of regeneration following spinal cord injury

Mutations of this gene have been associated with variety of inherited chondrodysplasias

Mutations in this gene have been associated with primary pulmonary hypertension| both familial and fenfluramine-associated| and with pulmonary venoocclusive disea

PLCA Polyclonal Antibody, 50ul Bio-Reaction Tube Variations in this gene mayThis gene encodes an enzyme that converts lysophosphatidic acid (LPA) into phosphatidic acid (PA). LPA and PA are two phospholipids involved in signal transduction and in lipid biosynthesis in cells. This enzyme localizes to the endoplasmic reticulum. This gene is located in the class III region of the human major histocompatibility complex. Alternative splicing results in two transcript variants encoding the same protein.

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