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and targeting CDK2 for proteolysis

Macrophage colony-stimulating factor 1 receptor encoded by CSF1R is the receptor for colony stimulating factor 1

This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors

Also highly expressed in ovarian and leukemia cell lines

UBR5 Polyclonal Antibody, 100ul Recombinant Ab Production Take your research to newUBR5 encodes a progestin induced protein, which belongs to the HECT (homology to E6 AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin protein ligases, targeting specific proteins for ubiquitin mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation.