Phospho-Bim (S59) Polyclonal Antibody, 100ul In vitro Transcription This particular family member contains

This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but

CREB3 (cAMP responsive element binding protein 3) encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins

Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells

The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain

Complex I removes electrons from NADH and passes them to the electron acceptor ubiquinone

Phospho-Bim (S59) Polyclonal Antibody, 100ul In vitro Transcription This particular family member containsBim Bod is a pro apoptotic protein belonging to the BH3 only group of Bcl 2 family members including Bad, Bid, Bik, Hrk, and Noxa that contain a BH3 domain but lack other conserved BH1 or BH2 domains. Bim induces apoptosis by binding to and antagonizing anti apoptotic members of the Bcl 2 family. Interactions have been observed with Bcl 2, Bcl xL, Mcl 1, Bcl w, Bfl 1, and BHRF 1. Bim functions in regulating apoptosis associated with thymocyte negative