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Axl Polyclonal Antibody, 100ul[BT-AP00783] Dry Bath This gene is located within

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Axl Polyclonal Antibody, 100ul[BT-AP00783] Dry Bath This gene is located withinThe protein encoded by AXL (AXL receptor tyrosine kinase) is a member of the Tyro3 Axl Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin like motifs at the N terminal, followed by two fibronectin type III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K dependent protein growth arrest specific 6 (Gas6).

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Description

This gene is located within the region of chromosome 9p that harbors tumor suppressor genes critical in carcinogenesis

and has glycosaminoglycan attachment sites in the acidic C-terminal region

and is negative on monocytes and activated T lymphocytes

|disease:Defects in C1S are the cause of selective C1s deficiency

Additionally| this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer

Axl Polyclonal Antibody, 100ul[BT-AP00783] Dry Bath This gene is located withinThe protein encoded by AXL (AXL receptor tyrosine kinase) is a member of the Tyro3 Axl Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin like motifs at the N terminal, followed by two fibronectin type III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K dependent protein growth arrest specific 6 (Gas6).

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