Phospho-5-LO (S272) Polyclonal Antibody, 50ul Stepper Mutations in this gene are

Mutations in this gene are associated with defects in organ development

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where it converts cholesteryl esters to free cholesterol for steroid hormone production

and medullablastomas

Several transcript variants encoding a few different isoforms have been found for this gene

Phospho-5-LO (S272) Polyclonal Antibody, 50ul Stepper Mutations in this gene areALOX5 encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The arachidonate 5 lipoxygenasen, which is expressed specifically in bone marrow derived cells, catalyzes the conversion of arachidonic acid to 5(S) hydroperoxy 6 trans 8,11,14 cis eicosatetraenoic acid, and further to the allylic epoxide 5(S) trans 7,9 trans 11,14 cis eicosatetrenoic acid (leukotriene A4). Leukotrienes