RFWD3 Polyclonal Antibody, 20ul Electronic Pipette Contributes to cell motility by

Contributes to cell motility by controlling actin dynamics

The microsatellite is polymorphic

and in a dimeric or multimeric form at the cell surface and in extracellular matrix

250mL*4pcs

Suitable for fluorescence microscopy

RFWD3 Polyclonal Antibody, 20ul Electronic Pipette Contributes to cell motility byRFWD3, also named as RNF201, is a E3 ubiquitin protein ligase that mediates the ubiquitination of p53 TP53 in the late response to DNA damage, and acts as a positive regulator of p53 TP53 stability, thereby regulating the G1 S DNA damage checkpoint. RFWD3 may act by catalyzing the formation of short polyubiquitin chains on p53 TP53 that are not targeted to the proteasome. In response to ionizing radiation, It interacts with MDM2 and enhances p53 TP53