KChIP1 Polyclonal Antibody, 100ul[BT-AP10626] Protein Analysis An N-terminal amphipathic helix

An N-terminal amphipathic helix

and cytoplasmic regions

Multiple alternatively spliced transcript variants have been found

This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues

One pseudogene is known to exist

KChIP1 Polyclonal Antibody, 100ul[BT-AP10626] Protein Analysis An N-terminal amphipathic helixThis gene encodes a member of the family of cytosolic voltage gated potassium (Kv) channel interacting proteins (KCNIPs), which belong to the neuronal calcium sensor (NCS) family of the calcium binding EF hand proteins. They associate with Kv4 alpha subunits to form native Kv4 channel complexes. The encoded protein may regulate rapidly inactivating (A type) currents, and hence neuronal membrane excitability, in response to changes in the concentration