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Raf-1(Phospho Tyr341) Polyclonal Antibody, 50ul Custom DNA Oligos Higher expression levels of RPS19

SKU: 52095199067

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Raf-1(Phospho Tyr341) Polyclonal Antibody, 50ul Custom DNA Oligos Higher expression levels of RPS19This gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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Description

Higher expression levels of RPS19 in some primary colon carcinomas compared to matched normal colon tissues has been observed

This encoded protein is known to associate with phytanoyl-CoA alpha-hydroxylase

The protein encoded by MC4R is a membrane-bound receptor and member of the melanocortin receptor family

This gene has been found fused to a variety of translocation partner genes in various leukemias| most notably the t(9

Within leukocyte population more abundant expression in neutrophils and eosinophils

Raf-1(Phospho Tyr341) Polyclonal Antibody, 50ul Custom DNA Oligos Higher expression levels of RPS19This gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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