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FRS2(Phospho Tyr436) Polyclonal Antibody, 100ul Oligo Pool This gene is a member

SKU: 46362919643

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FRS2(Phospho Tyr436) Polyclonal Antibody, 100ul Oligo Pool This gene is a memberAdapter protein that links FGR and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.,PTM: Phosphorylated on tyrosine residues upon stimulation by NGF.,PTM: Ubiquitinated when tyrosine phosphorylated and in a complex with GRB2. The unphosphorylated form is not subject to ubiquitination.,sequence Translated as stop.,Contains 1 IRS type

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Description

This gene is a member of the neuronal calcium sensor gene family| which encode calcium-binding proteins expressed predominantly in neurons

Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog

RCC2/TD-60 is also required for aurora B activation in vitro and localization of the CPC to centromeres

The encoded protein may play a role in the regulation of calcium levels inside the cell

and Familial dysautonomia

FRS2(Phospho Tyr436) Polyclonal Antibody, 100ul Oligo Pool This gene is a memberAdapter protein that links FGR and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.,PTM: Phosphorylated on tyrosine residues upon stimulation by NGF.,PTM: Ubiquitinated when tyrosine phosphorylated and in a complex with GRB2. The unphosphorylated form is not subject to ubiquitination.,sequence Translated as stop.,Contains 1 IRS type

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