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Rb Polyclonal Antibody, 20ul[BT-AP07688] Yeast Expression three ANK repeats

SKU: 45656589800

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Rb Polyclonal Antibody, 20ul[BT-AP07688] Yeast Expression three ANK repeatsThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

three ANK repeats

The binding of this protein to poly (A) promotes ribosome recruitment and translation initiation

NFKB1 encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein

Silica gel sealing washer inside the sealing cap eliminates liquid leakage

An important paralog of this gene is UBA52

Rb Polyclonal Antibody, 20ul[BT-AP07688] Yeast Expression three ANK repeatsThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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