MIP-5 Polyclonal Antibody, 100ul Shaker&Mixing TOP2A encodes a DNA topoisomerase

TOP2A encodes a DNA topoisomerase

This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains

The Smad proteins are subject to complex regulation by post-translational modifications

A pseudogene of this gene is also located on the short arm of chromosome 4

essential for T-cell proliferation and IFNG production in a PDCD1-independent manner

MIP-5 Polyclonal Antibody, 100ul Shaker&Mixing TOP2A encodes a DNA topoisomeraseThis gene is located in a cluster of similar genes in the same region of chromosome 17. These genes encode CC cytokines, which are secreted proteins characterized by two adjacent cysteines. The product of this gene is chemotactic for T cells and monocytes, and acts through C C chemokine receptor type 1 (CCR1). The proprotein is further processed into numerous smaller functional peptides. Naturally occurring readthrough transcripts occur from this gene