NT-4 Polyclonal Antibody, 50ul Diagnostic Probes & Oligos The protein localizes to the

The protein localizes to the endoplasmic reticulum (ER)

Members of this protein family contain ten conserved cysteine residues that form intra-molecular disulfide bonds

Overexpression of RhoA or activated RhoA in NIH 3T3 cells increased phosphorylation of MBS and MLC

in part by activating members of the E2F family of transcription factors

which are linked by a disulfide bridge

NT-4 Polyclonal Antibody, 50ul Diagnostic Probes & Oligos The protein localizes to theNTF4 is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of NTF4 is ubiquitous and less influenced by environmental signals. While knock outs of other neurotrophins including nerve growth factor, brain derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5 deficient mice only show minor cellular deficits and develop