KIRR1 Polyclonal Antibody, 20ul Antibody Development The lysine acetyltransferase 5 encoded

The lysine acetyltransferase 5 encoded by KAT5 belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein

The encoded protein plays a role in RNA metabolism by catalyzing the ATP-dependent conversion of the 3'-phosphate of RNA substrates to a 2'

This gene encodes a ribosomal protein that is a component of the 60S subunit

and thereby activate the cysteine protease cascade

and it prevents the assembly of the C3 and C5 convertase enzymes

KIRR1 Polyclonal Antibody, 20ul Antibody Development The lysine acetyltransferase 5 encodedNEPH1 is a member of the nephrin like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2; MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size and charge selective ultrafiltration (Sellin et al., 2003