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NuMA Polyclonal Antibody, 50ul High Speed Micro-Centrifuges which encodes over 1

SKU: 40587178985

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EUR162.00 EUR207.00

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NuMA Polyclonal Antibody, 50ul High Speed Micro-Centrifuges which encodes over 1NUMA1 encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of NUMA1 with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript

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Description

which encodes over 1

depending on stage of neuronal maturation and neuron type

Involved in formation of membrane ruffles and lamellipodia protrusions and in axon outgrowth

The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1

The protein binds to collagen IV and laminin

NuMA Polyclonal Antibody, 50ul High Speed Micro-Centrifuges which encodes over 1NUMA1 encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of NUMA1 with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript

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